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terminal O-glycans residues modification (via type 2 precursor disaccharide)

State Icon Reaction EC-Number Confidence maximal confidence score from EnzymeDetector
UDP-galactose + N-acetyl-beta-D-glucosaminyl-(1,3)-beta-D-galactosyl-(1,4)-N-acetyl-beta-D-glucosaminyl-R <=> nLc6Cer + H+ + UDP 2.4.1.38 beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase

UDP-galactose + N-acetyl-beta-D-glucosaminylglycopeptide <=> beta-D-galactosyl-1,4-N-acetyl-D-glucosaminyl-R + H+ + UDP 2.4.1.38 beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase
2.4.1.90 N-acetyllactosamine synthase


UDP-galactose + beta-D-galactosyl-1,4-N-acetyl-D-glucosaminyl-R <=> alpha-D-galactosyl-1,3-beta-D-galactosyl-1,4-N-acetyl-D-glucosaminyl-R + H+ + UDP 2.4.1.87 N-acetyllactosaminide 3-alpha-galactosyltransferase

UDP-galactose + beta-D-Gal-(1rarr4)-beta-D-GlcNAc-(1rarr3)-[beta-D-GlcNAc-(1rarr6)]-beta-D-Gal-(1rarr4)-beta-D-GlcNAc-R <=> nLc6Cer + H+ + UDP 2.4.1.38 beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase

UDP-N-acetyl-D-glucosamine + beta-D-galactosyl-1,4-N-acetyl-D-glucosaminyl-R <=> N-acetyl-beta-D-glucosaminyl-(1,3)-beta-D-galactosyl-(1,4)-N-acetyl-beta-D-glucosaminyl-R + H+ + UDP 2.4.1.149 N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase

UDP-N-acetyl-D-glucosamine + nLc6Cer <=> beta-D-Gal-(1rarr4)-beta-D-GlcNAc-(1rarr3)-[beta-D-GlcNAc-(1rarr6)]-beta-D-Gal-(1rarr4)-beta-D-GlcNAc-R + UDP + H+ 2.4.1.150 N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase

CMP-N-acetylneuraminate + beta-D-galactosyl-1,4-N-acetyl-D-glucosaminyl-R <=> N-acetyl-alpha-neuraminyl-(2rarr6)-beta-D-galactosyl-(1rarr4)-N-acetyl-beta-D-glucosaminyl-R + CMP + H+ 2.4.99.1 beta-galactoside alpha-(2,6)-sialyltransferase

CMP-N-acetylneuraminate + beta-D-galactosyl-1,4-N-acetyl-D-glucosaminyl-R <=> N-acetyl-alpha-neuraminyl-(2rarr3)-beta-D-galactosyl-(1rarr4)-N-acetyl-beta-D-glucosaminyl-R + CMP + H+ 2.4.99.6 N-acetyllactosaminide alpha-2,3-sialyltransferase

Visualization of the pathway